For Research Use Only · Not For Human or Veterinary Use · Not FDA-Approved

5-Amino-1MQ

Vial size

5-Amino-1MQ — independently assayed, batch-tested, and shipped from our fulfillment facility in San Antonio. Released only after an independent laboratory returns its results for the batch.

Select your pack size

Single

$74.99

$74.99 / vial

3-Pack

$213.72

$213.72 / vial

Save $11.25

6-Pack

$404.95

$404.95 / vial

Save $44.99

BEST DEAL

— About this compound

5-Amino-1MQ

5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule, cell-permeable inhibitor of nicotinamide N-methyltransferase (NNMT) — an enzyme that methylates nicotinamide using S-adenosylmethionine (SAM) as the methyl donor. Unlike the catalog’s peptides, it is a low-molecular-weight quinolinium compound, not an amino-acid chain.

 

Research interest centers on NNMT’s position at the intersection of the NAD+ salvage pathway and SAM-dependent methylation. Preclinical models have investigated whether NNMT inhibition shifts adipocyte energy expenditure and cellular NAD+ availability. Supplied for research use only.

— Mechanism

How it's been studied

Competitive inhibition of NNMT, reducing enzymatic methylation of nicotinamide. Proposed downstream effects in the literature include preservation of nicotinamide for NAD+ salvage and modulation of the cellular SAM/SAH methylation balance in adipocyte models.

—  How it’s made

From compound to your shelf

Every Nexa batch follows the same documented path. Five steps, every one verifiable.

01

Sourcing

Compound starts as a research-grade API.

Active pharmaceutical ingredient sourced from FDA-registered manufacturers. Identity confirmed against reference standard before any compounding begins.

02

Compounding

Sterile-filled in a US cleanroom.

Lyophilized in a cleanroom at our US facility. The powder format gives ≥24 months sealed stability — no cold-chain shipping required.

03

Verification

Every batch HPLC-tested.

Reverse-phase HPLC-UV (UV/MS for higher-MW peptides) confirms identity and purity for every batch before it leaves the lab. The chromatogram is archived.

04

Release

The batch is released against an independent assay.

No batch ships until an independent laboratory has returned its identity and purity results and the certificate is published in the COA library.

05

Dispatch

Ships from San Antonio in 48 hours.

Sealed vials with a QR code on the label that opens the COA library. Order before 2pm CT Monday–Thursday for same-day dispatch. UPS Ground, tracked + insured.