For Research Use Only · Not For Human or Veterinary Use · Not FDA-Approved
Vial size
5-Amino-1MQ — independently assayed, batch-tested, and shipped from our fulfillment facility in San Antonio. Released only after an independent laboratory returns its results for the batch.
Select your pack size
Single
$74.99
$74.99 / vial
3-Pack
$213.72
$213.72 / vial
Save $11.25
6-Pack
$404.95
$404.95 / vial
Save $44.99
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— About this compound
5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule, cell-permeable inhibitor of nicotinamide N-methyltransferase (NNMT) — an enzyme that methylates nicotinamide using S-adenosylmethionine (SAM) as the methyl donor. Unlike the catalog’s peptides, it is a low-molecular-weight quinolinium compound, not an amino-acid chain.
Research interest centers on NNMT’s position at the intersection of the NAD+ salvage pathway and SAM-dependent methylation. Preclinical models have investigated whether NNMT inhibition shifts adipocyte energy expenditure and cellular NAD+ availability. Supplied for research use only.
— Mechanism
Competitive inhibition of NNMT, reducing enzymatic methylation of nicotinamide. Proposed downstream effects in the literature include preservation of nicotinamide for NAD+ salvage and modulation of the cellular SAM/SAH methylation balance in adipocyte models.
— How it’s made
Every Nexa batch follows the same documented path. Five steps, every one verifiable.
01
Sourcing
Active pharmaceutical ingredient sourced from FDA-registered manufacturers. Identity confirmed against reference standard before any compounding begins.
02
Compounding
Lyophilized in a cleanroom at our US facility. The powder format gives ≥24 months sealed stability — no cold-chain shipping required.
03
Verification
Reverse-phase HPLC-UV (UV/MS for higher-MW peptides) confirms identity and purity for every batch before it leaves the lab. The chromatogram is archived.
04
Release
No batch ships until an independent laboratory has returned its identity and purity results and the certificate is published in the COA library.
05
Dispatch
Sealed vials with a QR code on the label that opens the COA library. Order before 2pm CT Monday–Thursday for same-day dispatch. UPS Ground, tracked + insured.