For Research Use Only · Not For Human or Veterinary Use · Not FDA-Approved
For Research Use Only · Not For Human or Veterinary Use · Not FDA-Approved
Vial size
MOTS-c — independently assayed, batch-tested, and shipped from our fulfillment facility in San Antonio. Released only after an independent laboratory returns its results for the batch.
Select your pack size
Single
$74.99
$74.99 / vial
3-Pack
$213.72
$213.72 / vial
Save $11.25
6-Pack
$404.95
$404.95 / vial
Save $44.99
BEST DEAL
— About this compound
MOTS-c (Mitochondrial Open Reading frame of the Twelve S rRNA type-c) is a 16-amino-acid peptide encoded within the mitochondrial DNA 12S rRNA region. It was the first mitochondrial-derived peptide identified with metabolic-regulator activity.
Unlike the larger family of nuclear-encoded signaling peptides, MOTS-c reflects intercommunication between the mitochondrial and nuclear genomes — a concept termed retrograde signaling. The peptide has become a focal point in mitochondrial-derived-peptide research.
— Mechanism
Translocates from the mitochondria to the nucleus under metabolic stress (glucose restriction, exercise). In the nucleus it regulates transcription of stress-responsive genes. Also activates AMPK signaling and modulates the folate-methionine cycle in cultured cells.
— How it’s made
Every Nexa batch follows the same documented path. Five steps, every one verifiable.
01
Sourcing
Active pharmaceutical ingredient sourced from FDA-registered manufacturers. Identity confirmed against reference standard before any compounding begins.
02
Compounding
Lyophilized in a cleanroom at our US facility. The powder format gives ≥24 months sealed stability — no cold-chain shipping required.
03
Verification
Reverse-phase HPLC-UV (UV/MS for higher-MW peptides) confirms identity and purity for every batch before it leaves the lab. The chromatogram is archived.
04
Release
No batch ships until an independent laboratory has returned its identity and purity results and the certificate is published in the COA library.
05
Dispatch
Sealed vials with a QR code on the label that opens the COA library. Order before 2pm CT Monday–Thursday for same-day dispatch. UPS Ground, tracked + insured.
